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Signature tagged mutagenesis in the functional genetic analysis of gastrointestinal pathogens

Signature tagged mutagenesis is a genetic approach that was developed to identify novel bacterial virulence factors. It is a negative selection method in which unique identification tags allow analysis of pools of mutants in mixed populations. The approach is particularly well suited to functional g...

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Autors principals: Cummins, Joanne, Gahan, Cormac G.M.
Format: Artigo
Idioma:Inglês
Publicat: Landes Bioscience 2012
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370953/
https://ncbi.nlm.nih.gov/pubmed/22555467
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/gmic.19578
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