Strand Length-Dependent Antimicrobial Activity and Membrane-Active Mechanism of Arginine- and Valine-Rich β-Hairpin-Like Antimicrobial Peptides

Antimicrobial peptides with amphipathic β-hairpin-like structures have potent antimicrobial properties and low cytotoxicity. The effect of VR or RV motifs on β-hairpin-like antimicrobial peptides has not been investigated. In this study, a series of β-hairpin-like peptides, Ac-C(VR)(n)(D)PG (RV)(n)C...

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Detalhes bibliográficos
Principais autores: Dong, Na, Ma, Qingquan, Shan, Anshan, Lv, Yinfeng, Hu, Wanning, Gu, Yao, Li, Yuzhi
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370809/
https://ncbi.nlm.nih.gov/pubmed/22391533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06327-11
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