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Bactericidal Activity of Multiple Combinations of Tigecycline and Colistin against NDM-1-Producing Enterobacteriaceae

The interaction between colistin and tigecycline against eight well-characterized NDM-1-producing Enterobacteriaceae strains was studied. Time-kill methodology was employed using a 4-by-4 exposure matrix with pharmacokinetically achievable free drug peak, trough, and average 24-h serum concentration...

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Bibliografiske detaljer
Main Authors: Albur, Mahableshwar, Noel, Alan, Bowker, Karen, MacGowan, Alasdair
Format: Artigo
Sprog:Inglês
Udgivet: American Society for Microbiology 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370758/
https://ncbi.nlm.nih.gov/pubmed/22391543
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.05682-11
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