Broad Phenotypic Cross-Resistance to Elvitegravir in HIV-Infected Patients Failing on Raltegravir-Containing Regimens

The failure of raltegravir (RAL) is generally associated with the selection of mutations at integrase position Y143, Q148, or N155. However, a relatively high proportion of failures occurs in the absence of these changes. Here, we report the phenotypic susceptibilities to RAL and elvitegravir (EVG)...

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Библиографические подробности
Главные авторы: Garrido, Carolina, Villacian, Jorge, Zahonero, Natalia, Pattery, Theresa, Garcia, Federico, Gutierrez, Felix, Caballero, Estrella, Van Houtte, Margriet, Soriano, Vincent, de Mendoza, Carmen
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Microbiology 2012
Предметы:
Antiviral Agents
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370736/
https://ncbi.nlm.nih.gov/pubmed/22450969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06170-11
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