Broad Phenotypic Cross-Resistance to Elvitegravir in HIV-Infected Patients Failing on Raltegravir-Containing Regimens

The failure of raltegravir (RAL) is generally associated with the selection of mutations at integrase position Y143, Q148, or N155. However, a relatively high proportion of failures occurs in the absence of these changes. Here, we report the phenotypic susceptibilities to RAL and elvitegravir (EVG)...

Disgrifiad llawn

Wedi'i Gadw mewn:
Manylion Llyfryddiaeth
Prif Awduron: Garrido, Carolina, Villacian, Jorge, Zahonero, Natalia, Pattery, Theresa, Garcia, Federico, Gutierrez, Felix, Caballero, Estrella, Van Houtte, Margriet, Soriano, Vincent, de Mendoza, Carmen
Fformat: Artigo
Iaith:Inglês
Cyhoeddwyd: American Society for Microbiology 2012
Pynciau:
Antiviral Agents
Mynediad Ar-lein:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370736/
https://ncbi.nlm.nih.gov/pubmed/22450969
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.06170-11
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