Antiinflammatory activity of soluble guanylate cyclase: cGMP-dependent down-regulation of P-selectin expression and leukocyte recruitment

Nitric oxide (NO) production by the vascular endothelium maintains an essential antiinflammatory, cytoprotective influence on the blood vessel wall. A key component of this activity is attributed to prevention of leukocyte–endothelial cell interactions, yet the underlying mechanisms remain unclear....

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Shranjeno v:
Bibliografske podrobnosti
izdano v:Proc Natl Acad Sci U S A
Main Authors: Ahluwalia, Amrita, Foster, Paul, Scotland, Ramona S., McLean, Peter G., Mathur, Anthony, Perretti, Mauro, Moncada, Salvador, Hobbs, Adrian J.
Format: Artigo
Jezik:Inglês
Izdano: National Academy of Sciences 2004
Teme:
Biological Sciences
Online dostop:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC337062/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/14742866/
https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.0304264101
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