L-Ficolin and Capsular Polysaccharide-Specific IgG in Cord Serum Contribute Synergistically to Opsonophagocytic Killing of Serotype III and V Group B Streptococci

Group B streptococci (GBS; Streptococcus agalactiae) are the most common cause of neonatal sepsis and meningitis. Serotype-specific IgG antibody is known to protect neonates against GBS infections by promoting opsonophagocytosis. The L-ficolin-mediated lectin pathway of the complement is also a pote...

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Detalhes bibliográficos
Main Authors: Fujieda, Mioko, Aoyagi, Youko, Matsubara, Kousaku, Takeuchi, Yasuhito, Fujimaki, Wakae, Matsushita, Misao, Bohnsack, John F., Takahashi, Shinji
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology 2012
Assuntos:
Bacterial Infections
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370578/
https://ncbi.nlm.nih.gov/pubmed/22451515
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/IAI.06232-11
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