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Overexpression of S4D Mutant of Leishmania donovani ADF/Cofilin Impairs Flagellum Assembly by Affecting Actin Dynamics

Leishmania, like other eukaryotes, contains large amounts of actin and a number of actin-related and actin binding proteins. Our earlier studies have shown that deletion of the gene corresponding to Leishmania actin-depolymerizing protein (ADF/cofilin) adversely affects flagellum assembly, intracell...

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Auteurs principaux: Kumar, Gaurav, Srivastava, Rashmi, Mitra, Kalyan, Sahasrabuddhe, Amogh A., Gupta, Chhitar M.
Format: Artigo
Langue:Inglês
Publié: American Society for Microbiology 2012
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Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370458/
https://ncbi.nlm.nih.gov/pubmed/22492507
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/EC.00013-12
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