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Gene replacement reveals that p115/SNARE interactions are essential for Golgi biogenesis

Functional characterization of protein interactions in mammalian systems has been hindered by the inability to perform complementation analyses in vivo. Here, we use functional replacement of the vesicle docking protein p115 to separate its essential from its nonessential interactions. p115 is requi...

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Detalhes bibliográficos
Main Authors: Puthenveedu, Manojkumar A., Linstedt, Adam D.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337039/
https://ncbi.nlm.nih.gov/pubmed/14736916
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0306373101
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