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Comparison of the kappa-opioid receptor antagonist DIPPA in tests of anxiety-like behavior between Wistar Kyoto and Sprague Dawley rats

RATIONALE: Recent evidence suggests a role for the dynorphin/ kappa-opioid receptor (KOR) system in the expression of stress-induced behaviors. Wistar Kyoto (WKY) rats exhibit increased depression-like and anxiety-like responses in behavioral tests compared to other strains and may be a model of com...

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Autors principals: Carr, Gregory V., Lucki, Irwin
Format: Artigo
Idioma:Inglês
Publicat: 2010
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370387/
https://ncbi.nlm.nih.gov/pubmed/20369354
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00213-010-1832-9
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