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Population pharmacokinetics and pharmacodynamics of escitalopram in overdose and the effect of activated charcoal

AIMS: To describe the pharmacokinetics and pharmacodynamics (PKPD) of escitalopram in overdose and its effect on QT prolongation, including the effectiveness of single dose activated charcoal (SDAC). METHODS: The data set included 78 escitalopram overdose events (median dose, 140 mg [10–560 mg]). SD...

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Bibliografski detalji
Glavni autori: van Gorp, Freek, Duffull, Stephen, Hackett, L Peter, Isbister, Geoffrey K
Format: Artigo
Jezik:Inglês
Izdano: Blackwell Science Inc 2012
Teme:
Online pristup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370344/
https://ncbi.nlm.nih.gov/pubmed/21883384
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1111/j.1365-2125.2011.04091.x
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