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Estimating hydration changes upon biomolecular reactions from osmotic stress, high pressure, and preferential hydration experiments

How do we estimate, from thermodynamic measurements, the number of water molecules adsorbed or released from biomolecules as a result of a biochemical process such as binding and allosteric effects? Volumetric and osmotic stress analyses are established methods for estimating water numbers; however,...

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Detalles Bibliográficos
Autor Principal: Shimizu, Seishi
Formato: Artigo
Idioma:Inglês
Publicado: National Academy of Sciences 2004
Assuntos:
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC337029/
https://ncbi.nlm.nih.gov/pubmed/14732698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0305836101
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