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A proton-coupled dynamic conformational switch in the HIV-1 dimerization initiation site kissing complex
In HIV type 1 (HIV-1), the dimerization initiation site (DIS) is the sequence primarily responsible for initiating the noncovalent linkage of two homologous strands of genomic RNA during viral assembly. The DIS loop contains an autocomplementary hexanucleotide sequence and forms a symmetric homodime...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
National Academy of Sciences
2004
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC337028/ https://ncbi.nlm.nih.gov/pubmed/14734802 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307966100 |
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