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DNA A-tract bending in three dimensions: Solving the dA(4)T(4) vs. dT(4)A(4) conundrum

DNA A-tracts have been defined as four or more consecutive A·T base pairs without a TpA step. When inserted in phase with the DNA helical repeat, bending is manifested macroscopically as anomalous migration on polyacrylamide gels, first observed >20 years ago. An unsolved conundrum is why DNA con...

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Detalhes bibliográficos
Main Authors: Stefl, Richard, Wu, Haihong, Ravindranathan, Sapna, Sklenář, Vladimír, Feigon, Juli
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337026/
https://ncbi.nlm.nih.gov/pubmed/14739342
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308143100
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