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ARF6 Activated by the LHCG Receptor through the Cytohesin Family of Guanine Nucleotide Exchange Factors Mediates the Receptor Internalization and Signaling

The luteinizing hormone chorionic gonadotropin receptor (LHCGR) is a G(s)-coupled GPCR that is essential for the maturation and function of the ovary and testis. LHCGR is internalized following its activation, which regulates the biological responsiveness of the receptor. Previous studies indicated...

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Detalhes bibliográficos
Main Authors: Kanamarlapudi, Venkateswarlu, Thompson, Aiysha, Kelly, Eamonn, López Bernal, Andrés
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Biochemistry and Molecular Biology 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370224/
https://ncbi.nlm.nih.gov/pubmed/22523074
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.362087
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