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Molecular dissection of water and glycerol permeability of the aquaglyceroporin from Plasmodium falciparum by mutational analysis

The selectivity of aquaporins for water and solutes is determined by pore diameter. Paradoxically, the wider pores of glycerol facilitators restrict water passage by an unknown mechanism. Earlier we characterized an aquaglyceroporin from Plasmodium falciparum with high permeability for both glycerol...

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Detalhes bibliográficos
Main Authors: Beitz, Eric, Pavlovic-Djuranovic, Slavica, Yasui, Masato, Agre, Peter, Schultz, Joachim E.
Formato: Artigo
Idioma:Inglês
Publicado em: National Academy of Sciences 2004
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC337022/
https://ncbi.nlm.nih.gov/pubmed/14734807
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0307295101
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