Apicomplexan Parasite, Eimeria falciformis, Co-opts Host Tryptophan Catabolism for Life Cycle Progression in Mouse

The obligate intracellular apicomplexan parasites, e.g. Toxoplasma gondii and Plasmodium species, induce an IFNγ-driven induction of host indoleamine 2,3-dioxygenase (IDO), the first and rate-limiting enzyme of tryptophan catabolism in the kynurenine pathway. Induction of IDO1 supposedly depletes ce...

Deskribapen osoa

Gorde:
Xehetasun bibliografikoak
Egile Nagusiak: Schmid, Manuela, Lehmann, Maik J., Lucius, Richard, Gupta, Nishith
Formatua: Artigo
Hizkuntza:Inglês
Argitaratua: American Society for Biochemistry and Molecular Biology 2012
Gaiak:
Microbiology
Sarrera elektronikoa:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370202/
https://ncbi.nlm.nih.gov/pubmed/22535959
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.351999
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