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A tautomeric zinc sensor for ratiometric fluorescence imaging: Application to nitric oxide-induced release of intracellular zinc

Zinc is an essential metal ion for human growth and development, the disruption of cellular Zn(2+) homeostasis being implicated in several major disorders including Alzheimer's disease, diabetes, and cancer. The molecular mechanisms of Zn(2+) physiology and pathology are insufficiently understo...

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Главные авторы: Chang, Christopher J., Jaworski, Jacek, Nolan, Elizabeth M., Sheng, Morgan, Lippard, Stephen J.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2004
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Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC337018/
https://ncbi.nlm.nih.gov/pubmed/14734801
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0308079100
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