Cooperation of Nuclear Fibroblast Growth Factor Receptor 1 and Nurr1 Offers New Interactive Mechanism in Postmitotic Development of Mesencephalic Dopaminergic Neurons

Experiments in mice deficient for Nurr1 or expressing the dominant-negative FGF receptor (FGFR) identified orphan nuclear receptor Nurr1 and FGFR1 as essential factors in development of mesencephalic dopaminergic (mDA) neurons. FGFR1 affects brain cell development by two distinct mechanisms. Activat...

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Главные авторы: Baron, Olga, Förthmann, Benjamin, Lee, Yu-Wei, Terranova, Christopher, Ratzka, Andreas, Stachowiak, Ewa K., Grothe, Claudia, Claus, Peter, Stachowiak, Michal K.
Формат: Artigo
Язык:Inglês
Опубликовано: American Society for Biochemistry and Molecular Biology 2012
Предметы:
Cell Biology
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370168/
https://ncbi.nlm.nih.gov/pubmed/22514272
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.347831
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