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CIKS/Act1-mediated signaling by IL-17 cytokines in context: Implications for how a CIKS gene variant may predispose to psoriasis

Psoriasis is a relapsing skin disease characterized by abnormal keratinocyte proliferation and differentiation and by an influx of inflammatory immune cells. Recently IL-17 cytokines have been strongly implicated as critical for the pathogenesis of this disease. IL-17A (a.k.a. IL-17) and IL-17F are...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Sønder, Søren Ulrik, Paun, Andrea, Ha, Hye-Lin, Johnson, Peter F., Siebenlist, Ulrich
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370149/
https://ncbi.nlm.nih.gov/pubmed/22581863
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1103233
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