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Complement-dependent injury and protection in a murine model of acute DSS-induced colitis()

Complement plays a key role in the pathophysiology of many inflammatory diseases, and here we investigated the role of complement in the pathogenesis of inflammatory bowel disease (IBD). Compared to wild type (wt) mice, mice deficient in C3 or factor B (fB) were protected from acute DSS-induced coli...

Ausführliche Beschreibung

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Bibliographische Detailangaben
Hauptverfasser: Schepp-Berglind, Jennifer, Atkinson, Carl, Elvington, Michelle, Qiao, Fei, Mannon, Peter, Tomlinson, Stephen
Format: Artigo
Sprache:Inglês
Veröffentlicht: 2012
Schlagworte:
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3370107/
https://ncbi.nlm.nih.gov/pubmed/22566568
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4049/jimmunol.1200553
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