Uracil-Containing DNA in Drosophila: Stability, Stage-Specific Accumulation, and Developmental Involvement

Base-excision repair and control of nucleotide pools safe-guard against permanent uracil accumulation in DNA relying on two key enzymes: uracil–DNA glycosylase and dUTPase. Lack of the major uracil–DNA glycosylase UNG gene from the fruit fly genome and dUTPase from fruit fly larvae prompted the hypo...

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Detalhes bibliográficos
Main Authors: Muha, Villő, Horváth, András, Békési, Angéla, Pukáncsik, Mária, Hodoscsek, Barbara, Merényi, Gábor, Róna, Gergely, Batki, Júlia, Kiss, István, Jankovics, Ferenc, Vilmos, Péter, Erdélyi, Miklós, Vértessy, Beáta G.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369950/
https://ncbi.nlm.nih.gov/pubmed/22685418
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002738
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