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Uracil-Containing DNA in Drosophila: Stability, Stage-Specific Accumulation, and Developmental Involvement
Base-excision repair and control of nucleotide pools safe-guard against permanent uracil accumulation in DNA relying on two key enzymes: uracil–DNA glycosylase and dUTPase. Lack of the major uracil–DNA glycosylase UNG gene from the fruit fly genome and dUTPase from fruit fly larvae prompted the hypo...
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| Autors principals: | , , , , , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Public Library of Science
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369950/ https://ncbi.nlm.nih.gov/pubmed/22685418 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002738 |
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