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Limits to the Rate of Adaptive Substitution in Sexual Populations

In large populations, many beneficial mutations may be simultaneously available and may compete with one another, slowing adaptation. By finding the probability of fixation of a favorable allele in a simple model of a haploid sexual population, we find limits to the rate of adaptive substitution, [I...

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Bibliografiske detaljer
Main Authors: Weissman, Daniel B., Barton, Nicholas H.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369949/
https://ncbi.nlm.nih.gov/pubmed/22685419
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pgen.1002740
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