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Keratin 8/18 Regulation of Cell Stiffness-Extracellular Matrix Interplay through Modulation of Rho-Mediated Actin Cytoskeleton Dynamics

Cell mechanical activity generated from the interplay between the extracellular matrix (ECM) and the actin cytoskeleton is essential for the regulation of cell adhesion, spreading and migration during normal and cancer development. Keratins are the intermediate filament (IF) proteins of epithelial c...

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Detalles Bibliográficos
Main Authors: Bordeleau, François, Myrand Lapierre, Marie-Eve, Sheng, Yunlong, Marceau, Normand
Formato: Artigo
Idioma:Inglês
Publicado: Public Library of Science 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369864/
https://ncbi.nlm.nih.gov/pubmed/22685604
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038780
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