Mesenchymal Stromal Cells Improve Salivary Function and Reduce Lymphocytic Infiltrates in Mice with Sjögren's-Like Disease

BACKGROUND: Non-obese diabetic (NOD) mice develop Sjögren's-like disease (SS-like) with loss of saliva flow and increased lymphocytic infiltrates in salivary glands (SGs). There are recent reports using multipotent mesenchymal stromal cells (MSCs) as a therapeutic strategy for autoimmune diseas...

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Detalhes bibliográficos
Main Authors: Khalili, Saeed, Liu, Younan, Kornete, Mara, Roescher, Nienke, Kodama, Shohta, Peterson, Alan, Piccirillo, Ciriaco A., Tran, Simon D.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369846/
https://ncbi.nlm.nih.gov/pubmed/22685592
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038615
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