Binding Modes of Thioflavin T Molecules to Prion Peptide Assemblies Identified by Using Scanning Tunneling Microscopy

[Image: see text] The widely used method to monitor the aggregation process of amyloid peptide is thioflavin T (ThT) assay, while the detailed molecular mechanism is still not clear. In this work, we report here the direct identification of the binding modes of ThT molecules with the prion peptide G...

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Main Authors: Mao, Xiaobo, Guo, Yuanyuan, Wang, Chenxuan, Zhang, Min, Ma, Xiaojing, Liu, Lei, Niu, Lin, Zeng, Qingdao, Yang, Yanlian, Wang, Chen
Format: Artigo
Jezik:Inglês
Izdano: American Chemical Society 2011
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369759/
https://ncbi.nlm.nih.gov/pubmed/22778872
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200006h
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