Label-Free Visualization of Ultrastructural Features of Artificial Synapses via Cryo-EM

[Image: see text] The ultrastructural details of presynapses formed between artificial substrates of submicrometer silica beads and hippocampal neurons are visualized via cryo-electron microscopy (cryo-EM). The silica beads are derivatized by poly-d-lysine or lipid bilayers. Molecular features known...

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Main Authors: Gopalakrishnan, Gopakumar, Yam, Patricia T., Madwar, Carolin, Bostina, Mihnea, Rouiller, Isabelle, Colman, David R., Lennox, R. Bruce
Format: Artigo
Sprog:Inglês
Udgivet: American Chemical Society 2011
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369721/
https://ncbi.nlm.nih.gov/pubmed/22860164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn200094j
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