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Subtle Recognition of 14-Base Pair DNA Sequences via Threading Polyintercalation

[Image: see text] Small molecules that bind DNA in a sequence-specific manner could act as antibiotic, antiviral, or anticancer agents because of their potential ability to manipulate gene expression. Our laboratory has developed threading polyintercalators based on 1,4,5,8-naphthalene diimide (NDI)...

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Hlavní autoři: Rhoden Smith, Amy, Ikkanda, Brian A., Holman, Garen G., Iverson, Brent L.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Chemical Society 2012
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369501/
https://ncbi.nlm.nih.gov/pubmed/22554127
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/bi300317n
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