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Pharmacological Unmasking Microarray Approach-Based Discovery of Novel DNA Methylation Markers for Hepatocellular Carcinoma

DNA methylation is one of the main epigenetic mechanisms and hypermethylation of CpG islands at tumor suppressor genes switches off these genes. To find novel DNA methylation markers in hepatocellular carcinoma (HCC), we performed pharmacological unmasking (treatment with 5-aza-2'-deoxycytidine...

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Detalles Bibliográficos
Main Authors: Jung, Namhee, Won, Jae Kyung, Kim, Baek-Hui, Suh, Kyung Suk, Jang, Ja-June, Kang, Gyeong Hoon
Formato: Artigo
Idioma:Inglês
Publicado: The Korean Academy of Medical Sciences 2012
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369444/
https://ncbi.nlm.nih.gov/pubmed/22690089
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3346/jkms.2012.27.6.594
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