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Inhibition of HDAC9 Increases T Regulatory Cell Function and Prevents Colitis in Mice
BACKGROUND & AIMS: Foxp3+ T regulatory cells (Tregs) help prevent autoimmunity, and increases in their numbers of functions could decrease the development of inflammatory bowel disease. Like other cells, Foxp3+ Tregs express histone/protein deacetylases (HDACs), which regulate chromatin remodeli...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2009
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3369426/ https://ncbi.nlm.nih.gov/pubmed/19879272 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1053/j.gastro.2009.10.037 |
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