Physiopathology of Bone Modifications in β-Thalassemia

β-thalassemia major (βTM) or Cooley anemia is characterized by significantly reduced or absent synthesis of β-globin chains, which induces important pathologic consequences including hemolytic anemia, altered erythropoiesis, and bone marrow overstimulation. The pathogenesis of bone changes in patien...

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Bibliografiske detaljer
Main Authors: Perisano, Carlo, Marzetti, Emanuele, Spinelli, Maria Silvia, Callà, Cinzia Anna Maria, Graci, Calogero, Maccauro, Giulio
Format: Artigo
Sprog:Inglês
Udgivet: Hindawi Publishing Corporation 2012
Fag:
Review Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369393/
https://ncbi.nlm.nih.gov/pubmed/22693660
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/320737
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