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Cell Membrane–associated Heparan Sulfate Is a Receptor for Prototype Foamy Virus in Human, Monkey, and Rodent Cells

Foamy viruses (FVs) (spumaretroviruses) are good alternative to retroviruses as gene therapy vector. Despite four decades since the discovery of FV, its receptor molecule is still unknown. FV vector transduction of human CD34(+) cells was inhibited by culture with fibronectin. Because fibronectin co...

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Detalhes bibliográficos
Main Authors: Nasimuzzaman, Md, Persons, Derek A
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369305/
https://ncbi.nlm.nih.gov/pubmed/22434139
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.41
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