Expression of Immunomodulatory Neutrophil-activating Protein of Helicobacter pylori Enhances the Antitumor Activity of Oncolytic Measles Virus

Helicobacter pylori neutrophil-activating protein (NAP) is a major virulence factor and powerful inducer of inflammatory reaction and Th1-polarized immune response. Here, we evaluated the therapeutic efficacy of measles virus (MV) strains engineered to express secretory NAP forms against metastatic...

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Detalhes bibliográficos
Main Authors: Iankov, Ianko D, Allen, Cory, Federspiel, Mark J, Myers, Rae M, Peng, Kah Whye, Ingle, James N, Russell, Stephen J, Galanis, Evanthia
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group 2012
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369290/
https://ncbi.nlm.nih.gov/pubmed/22334023
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/mt.2012.4
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