Hepatocyte growth factor gene therapy enhances infiltration of macrophages and may induce kidney repair in db/db mice as a model of diabetes

AIMS/HYPOTHESIS: We previously demonstrated hepatocyte growth factor (HGF) gene therapy was able to induce regression of glomerulosclerosis in diabetic nephropathy through local reparative mechanisms. The aim of this study was to test whether bone-marow-derived cells are also involved in this HGF-in...

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Main Authors: Flaquer, M., Franquesa, M., Vidal, A., Bolaños, N., Torras, J., Lloberas, N., Herrero-Fresneda, I., Grinyó, J. M., Cruzado, J. M.
Format: Artigo
Sprog:Inglês
Udgivet: Springer-Verlag 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369134/
https://ncbi.nlm.nih.gov/pubmed/22460762
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s00125-012-2535-z
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