Tumor dosimetry using [(124)I]m-iodobenzylguanidine microPET/CT for [(131)I]m- iodobenzylguanidine treatment of neuroblastoma in a murine xenograft model

PURPOSE: [(124)I]m-iodobenzylguanidine ((124)I-mIBG) provides a quantitative tool for pretherapy tumor imaging and dosimetry when performed before [(131)I]m-iodobenzylguanidine ((131)I-mIBG) targeted radionuclide therapy of neuroblastoma. (124)I (T(1/2)=4.2d) has a comparable half-life to that of (1...

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Main Authors: Seo, Youngho, Gustafson, W. Clay, Dannoon, Shorouk F., Nekritz, Erin A., Lee, Chang-Lae, Murphy, Stephanie T., VanBrocklin, Henry F., Hernandez-Pampaloni, Miguel, Haas-Kogan, Daphne A., Weiss, William A., Matthay, Katherine K.
Format: Artigo
Sprog:Inglês
Udgivet: 2012
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Article
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3369020/
https://ncbi.nlm.nih.gov/pubmed/22382618
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1007/s11307-012-0552-4
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