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Integrin α9β1 promotes malignant tumor growth and metastasis by potentiating epithelial-mesenchymal transition

The integrin α9β1 binds a number of extracellular matrix components to mediate cell adhesion, migration and tissue invasion. Although expressed in variety of normal human cells including endothelium, it is also expressed in cancer cells. We have previously shown that α9β1 binds VEGF-A to facilitate...

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Bibliographic Details
Main Authors: Gupta, Shiv K, Oommen, Saji, Aubry, Marie-Christine, Williams, Brian P., Vlahakis, Nicholas E
Format: Artigo
Language:Inglês
Published: 2012
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368989/
https://ncbi.nlm.nih.gov/pubmed/22370635
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/onc.2012.41
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