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Retrotransposons as a major source of epigenetic variations in the mammalian genome

Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements, such as intracisternal A-particles (IAPs) associated with the Agouti and Axin-fused loci, partially escape this repression mechanism. The levels of this repression are also variable among individuals with...

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Detalhes bibliográficos
Main Authors: Ekram, Muhammad B., Kang, Keunsoo, Kim, Hana, Kim, Joomyeong
Formato: Artigo
Idioma:Inglês
Publicado em: Landes Bioscience 2012
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368820/
https://ncbi.nlm.nih.gov/pubmed/22415164
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19462
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