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Retrotransposons as a major source of epigenetic variations in the mammalian genome
Transcription of retrotransposons is usually repressed by DNA methylation, but a few elements, such as intracisternal A-particles (IAPs) associated with the Agouti and Axin-fused loci, partially escape this repression mechanism. The levels of this repression are also variable among individuals with...
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| Main Authors: | , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
Landes Bioscience
2012
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368820/ https://ncbi.nlm.nih.gov/pubmed/22415164 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.4161/epi.19462 |
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