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Connective tissue growth factor in tumor pathogenesis

Key roles for connective tissue growth factor (CTGF/CCN2) are demonstrated in the wound repair process where it promotes myofibroblast differentiation and angiogenesis. Similar mechanisms are active in tumor-reactive stroma where CTGF is expressed. Other potential roles include prevention of hypoxia...

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Détails bibliographiques
Auteurs principaux: Jacobson, Annica, Cunningham, Janet L
Format: Artigo
Langue:Inglês
Publié: BioMed Central 2012
Sujets:
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368788/
https://ncbi.nlm.nih.gov/pubmed/23259759
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/1755-1536-5-S1-S8
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