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Photochemically Initiated Intracellular Astrocytic Calcium Waves in Living Mice Using Two-Photon Uncaging of IP(3)

[Image: see text] We have developed a caged IP(3) analogue for two-photon photolysis in living animals. This probe is a cell permeable version and was coloaded with a fluorescent Ca(2+) dye into astrocytes in layer 1 of the somatosensory cortex of anesthetized mice. Two-photon irradiation of single...

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Autors principals: Crowe, Sarah E., Kantevari, Srinivas, Ellis-Davies, Graham C. R.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2010
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368680/
https://ncbi.nlm.nih.gov/pubmed/22778846
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/cn100052v
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