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What can humans learn from flies about adenomatous polyposis coli?
Somatic or inherited mutations in the adenomatous polyposis coli (APC) gene are a frequent cause of colorectal cancer in humans. APC protein has an important tumor suppression function to reduce cellular levels of the signaling protein β-catenin and, thereby, inhibit β-catenin and T-cell-factor-medi...
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| Main Authors: | , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2002
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368605/ https://ncbi.nlm.nih.gov/pubmed/12210511 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/bies.10152 |
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