The Adipocyte-Derived Hormone Leptin Has Proliferative Actions on Androgen-Resistant Prostate Cancer Cells Linking Obesity to Advanced Stages of Prostate Cancer

Background. Because obesity may be a risk factor for prostate cancer, we investigated proliferative effects of adipocytes-derived hormone leptin on human prostate cancer cells and assessed the role of mitogen-activated protein kinase (MAPK) signaling pathway in mediating these actions. Material and...

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Autors principals: Hoda, M. Raschid, Theil, Gerit, Mohammed, Nasreldin, Fischer, Kersten, Fornara, Paolo
Format: Artigo
Idioma:Inglês
Publicat: Hindawi Publishing Corporation 2012
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Research Article
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368429/
https://ncbi.nlm.nih.gov/pubmed/22690216
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1155/2012/280386
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