Paradoxical Effects of Rapamycin on Experimental House Dust Mite-Induced Asthma

The mammalian target of rapamycin (mTOR) modulates immune responses and cellular proliferation. The objective of this study was to assess whether inhibition of mTOR with rapamycin modifies disease severity in two experimental murine models of house dust mite (HDM)-induced asthma. In an induction mod...

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Detalhes bibliográficos
Main Authors: Fredriksson, Karin, Fielhaber, Jill A., Lam, Jonathan K., Yao, Xianglan, Meyer, Katharine S., Keeran, Karen J., Zywicke, Gayle J., Qu, Xuan, Yu, Zu-Xi, Moss, Joel, Kristof, Arnold S., Levine, Stewart J.
Formato: Artigo
Idioma:Inglês
Publicado em: Public Library of Science 2012
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368343/
https://ncbi.nlm.nih.gov/pubmed/22685525
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0033984
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