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The Role of Membrane Stiffness and Actin Turnover on the Force Exerted by DRG Lamellipodia
We used optical tweezers to analyze the effect of jasplakinolide and cyclodextrin on the force exerted by lamellipodia from developing growth cones (GCs) of isolated dorsal root ganglia (DRG) neurons. We found that 25 nM of jasplakinolide, which is known to inhibit actin filament turnover, reduced b...
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| Main Authors: | , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
The Biophysical Society
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3368133/ https://ncbi.nlm.nih.gov/pubmed/22713560 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.036 |
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