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Investigation of Ebola VP40 Assembly and Oligomerization in Live Cells Using Number and Brightness Analysis

Ebola virus assembles and buds from the inner leaflet of the plasma membrane of mammalian cells, which is primarily attributed to its major matrix protein VP40. Oligomerization of VP40 has been shown to be essential to the life cycle of the virus including formation of virions from infected cells. T...

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Bibliographic Details
Main Authors: Adu-Gyamfi, Emmanuel, Digman, Michelle A., Gratton, Enrico, Stahelin, Robert V.
Format: Artigo
Language:Inglês
Published: The Biophysical Society 2012
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC3368128/
https://ncbi.nlm.nih.gov/pubmed/22713567
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.bpj.2012.04.022
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