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Altered Circulating Levels of Matrix Metalloproteinases and Inhibitors Associated with Elevated Type 2 Cytokines in Lymphatic Filarial Disease

BACKGROUND: Infection with Wuchereria bancrofti can cause severe disease characterized by subcutaneous fibrosis and extracellular matrix remodeling. Matrix metalloproteinases (MMPs) are a family of enzymes governing extracellular remodeling by regulating cellular homeostasis, inflammation, and tissu...

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Autors principals: Anuradha, Rajamanickam, George, Jovvian P., Pavankumar, Nathella, Kumaraswami, Vasanthapuram, Nutman, Thomas B., Babu, Subash
Format: Artigo
Idioma:Inglês
Publicat: Public Library of Science 2012
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Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367978/
https://ncbi.nlm.nih.gov/pubmed/22679524
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pntd.0001681
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