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Hierarchical Control on Polyene Macrolide Biosynthesis: PimR Modulates Pimaricin Production via the PAS-LuxR Transcriptional Activator PimM

Control of polyene macrolide production in Streptomyces natalensis is mediated by the transcriptional activator PimR. This regulator combines an N-terminal domain corresponding to the Streptomyces antibiotic regulatory protein (SARP) family of transcriptional activators with a C-terminal half homolo...

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Main Authors: Santos-Aberturas, Javier, Vicente, Cláudia M., Payero, Tamara D., Martín-Sánchez, Lara, Cañibano, Carmen, Martín, Juan F., Aparicio, Jesús F.
Format: Artigo
Sprog:Inglês
Udgivet: Public Library of Science 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367932/
https://ncbi.nlm.nih.gov/pubmed/22693644
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1371/journal.pone.0038536
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