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RhoH is critical for cell-microenvironment interactions in chronic lymphocytic leukemia in mice and humans
Trafficking of B-cell chronic lymphocytic leukemia (CLL) cells to the bone marrow and interaction with supporting stromal cells mediates important survival and proliferation signals. Previous studies have demonstrated that deletion of Rhoh led to a delayed disease onset in a murine model of CLL. Her...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado: |
American Society of Hematology
2012
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| Assuntos: | |
| Acceso en liña: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367874/ https://ncbi.nlm.nih.gov/pubmed/22474251 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2011-12-395939 |
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