A conserved heptamer upstream of the IgH promoter region octamer can be the site of a coordinate protein-DNA interaction.

Immunoglobulin genes contain a conserved eight base sequence element 5' to the site of transcription initiation. This octamer can serve as a site for the binding of nuclear proteins which are presumably involved in the cell type specific expression of this family of genes. In studying the bindi...

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Bibliographic Details
Main Authors: Landolfi, N F, Yin, X M, Capra, J D, Tucker, P W
Format: Artigo
Language:Inglês
Published: 1988
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC336781/
https://ncbi.nlm.nih.gov/pubmed/3387240
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