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A conserved heptamer upstream of the IgH promoter region octamer can be the site of a coordinate protein-DNA interaction.

Immunoglobulin genes contain a conserved eight base sequence element 5' to the site of transcription initiation. This octamer can serve as a site for the binding of nuclear proteins which are presumably involved in the cell type specific expression of this family of genes. In studying the binding of...

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Publicat a:Nucleic Acids Res
Autors principals: Landolfi, N F, Yin, X M, Capra, J D, Tucker, P W
Format: Artigo
Idioma:Inglês
Publicat: Oxford University Press 1988
Accés en línia:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC336781/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/3387240/
https://ncbi.nlm.nih.govhttps://doi.org/10.1093/nar/16.12.5503
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