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Transferrin-PEG-PE modified dexamethasone conjugated cationic lipid carrier mediated gene delivery system for tumor-targeted transfection

BACKGROUND: The main barriers to non-viral gene delivery include cellular and nuclear membranes. As such, the aim of this study was to develop a type of vector that can target cells through receptor-mediated pathways and by using nuclear localization signal (NLS) to increase the nuclear uptake of ge...

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Autori principali: Wang, Wei, Zhou, Fang, Ge, Linfu, Liu, Ximin, Kong, Fansheng
Natura: Artigo
Lingua:Inglês
Pubblicazione: Dove Medical Press 2012
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Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367492/
https://ncbi.nlm.nih.gov/pubmed/22679364
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2147/IJN.S31915
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