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A zebrafish Notum homolog specifically blocks the Wnt/β-catenin signaling pathway

Multiple developmental processes require tightly controlled Wnt signaling, and its misregulation leads to congenital abnormalities and diseases. Glypicans are extracellular proteins that modulate the Wnt pathway. In addition to interacting with Wnts, these glycosophosphotidylinositol (GPI)-anchored,...

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Bibliografiske detaljer
Main Authors: Flowers, G. Parker, Topczewska, Jolanta M., Topczewski, Jacek
Format: Artigo
Sprog:Inglês
Udgivet: Company of Biologists 2012
Fag:
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3367448/
https://ncbi.nlm.nih.gov/pubmed/22669824
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.063206
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