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The developmental dismantling of pluripotency is reversed by ectopic Oct4 expression
The transcription factors Nanog and Oct4 regulate pluripotency in the pre-implantation epiblast and in derivative embryonic stem cells. During post-implantation development, the precise timing and mechanism of the loss of pluripotency is unknown. Here, we show that in the mouse, pluripotency is exti...
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| Main Authors: | , , , , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
Company of Biologists
2012
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3367440/ https://ncbi.nlm.nih.gov/pubmed/22669820 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1242/dev.078071 |
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